Astrea Bioseparations (UK) was founded in 1987. Its predecessor was Affinity Chromatography Ltd, which spun off from the University of Cambridge (UK) to focus on the R&D and production of adsorption media.

The two core patented technologies (products) of Astrea Bioseparations—Mimetic ligand® and PuraBead®—serve as the cornerstone of the company’s product portfolio. To date, 21 marketed products (approved by the FDA/EMA) have utilized Astrea Bioseparations’ products for commercial manufacturing, including those from multinational corporations and emerging biotechnology companies.

In recent years, with the rise of the Cell & Gene Therapy (CGT) field, the purification of viral vectors has faced numerous technical bottlenecks. Astrea Bioseparations is committed to developing AstreAdept®, a new type of bioseparation material for the efficient purification of viral vectors.

AstreAdept® is an electrospun composite nanofiber chromatographic membrane with a large open structure. It enables almost instantaneous binding of large targets (including viral vectors) to a much larger binding surface area.

Nereus LentiHERO is the first commercial product adopting AstreAdept® technology. This new chromatographic technology addresses the issues of capacity and process time associated with traditional bioseparation tools. It operates under physiological pH and salt concentration conditions, which preserves the integrity and quality of lentiviral (LV) particles. Meanwhile, it offers high binding capacity and high recovery rate, enabling higher yields from raw materials.

The application of AstreAdept® technology allows biopharmaceutical manufacturers to accelerate processes, improve efficiency, reduce the use of buffers, and lower costs. This achieves a faster, more environmentally friendly, and more cost-effective purification process, fully meeting the needs of today’s biotherapeutic innovation.

Featured Products of Astrea Bioseparations:

· Lentiviral Vector Purification Media: Nereus LentiHERO®

· Endotoxin Removal Media: EtoxiClear®

· Host Cell Protein (HCP) Removal Media: HCPure?

· Glycoprotein Affinity Media: Aminophenylboronate P6XL

· Insulin Purification Media: Insulin Adsorbent

· Albumin & Fusion Albumin Purification Media: Mimetic Blue® & AlbuPure®

In January 2024, Beijing XMJ Scientific Co., Ltd. officially became the first-level authorized distributor of Astrea Bioseparations in China. Leveraging Astrea Bioseparations’ strong technological advantages and XMJ’s rich and professional products and services, this collaboration will help provide more high-quality service and product options for domestic biopharmaceutical enterprises.

If you are interested in the above products, please feel free to send email to info@xmjsci.com or visit XMJ’s official website rmb365.cn for inquiries and orders.

Beijing XMJ Scientific Co., Ltd. (hereinafter referred to as XMJ) was founded in 2006 by professionals in the biological field who returned to China after studying in the United States. It is a high-tech company integrating the sales of imported reagents, technical services and contract development, aiming to provide first-class products and services for the development of life sciences.

Over the 18 years since its establishment, XMJ has diligently and practically integrated high-quality global resources, providing customers with a wealth of professional products and services. These include basic components of cell culture media, GMP-grade transfection reagents, various pharmacopoeia-grade biochemical reagents, purification media, GMP-grade nucleases, HCP/HCD detection kits, detection kits for residual impurities in bioprocesses (such as Protein A, BSA, and MVM), protein characterization and analysis kits, injectable pharmaceutical excipients, antigens/antibodies/substrates, as well as services for the validation of host protein residue detection kits and the development of customized kits. These products and services meet the one-stop needs from research and development to production in aspects like cell culture, transfection, purification processes, quality control, formulation, and drug evaluation.

XMJ has import and export qualifications and its own international logistics system. It has established long-term and stable cooperative relationships with more than 40 domestic and foreign suppliers of reagents, instruments, raw and auxiliary materials, and technical services, and has brought together dozens of well-known domestic and foreign brands, including AppliChem, Cygnus, Pfanstiehl, c-LEcta, Mirus, Astrea Bioseparations, KPL, and ZF Biology.

With the development of its business, XMJ has successively set up branches in cities such as Shanghai, Guangzhou, Chengdu, Wuhan, and Shenzhen. It has become a designated supplier for the procurement platforms of domestic biopharmaceutical enterprises, diagnostic enterprises, well-known multinational pharmaceutical enterprises, as well as major universities and research institutions, and has won the support and trust of numerous customers.